GREGoR: accelerating genomics for rare diseases

Author(s)

Moez Dawood

Ben Heavner

Marsha M Wheeler

Rachel A Ungar

Jonathan LoTempio

Laurens Wiel

Seth Berger

Jonathan A Bernstein

Jessica X Chong

Emmanuele C Delot

Evan E Eichler

James R Lupski

Ali Shojaie

Michael E Talkowski

Alex H Wagner

Chia-Lin Wei

Christopher Wellington

Matthew T Wheeler

GREGoR Partner Members

Claudia M B Carvalho

Richard A Gibbs

Casey A Gifford

Susanne May

Danny E Miller

Heidi L Rehm

Kaitlin E Samocha

Fritz J Sedlazeck

Eric Vilain

Anne O'Donnell-Luria

Jennifer E Posey

Lisa H Chadwick

Michael J Bamshad

Stephen B Montgomery

Journal Name

Nature

Publication Date

November 12, 2025

DOI

10.1038/s41586-025-09613-8

GREGoR: accelerating genomics for rare diseases

Disentangling cell-intrinsic and cell-extrinsic factors underlying evolution.

Fine-scale diversity and extensiverecombination in a quasisexual bacterialpopulation occupying a broad niche

A fully-automated method discovers loss of mouse-lethal and human-monogenic disease genes in 58 mammals

GREGoR: accelerating genomics for rare diseases

More Publications

Disentangling cell-intrinsic and cell-extrinsic factors underlying evolution.

Fine-scale diversity and extensiverecombination in a quasisexual bacterialpopulation occupying a broad niche

A fully-automated method discovers loss of mouse-lethal and human-monogenic disease genes in 58 mammals